Insulin sensitization by hepatic FoxO deletion is insufficient to lower atherosclerosis in mice

BACKGROUND–: Type 2 diabetes is associated with an increased risk of atherosclerotic cardiovascular disease. It has been suggested that insulin resistance underlies this link, possibly by altering the functions of cells in the artery wall. We aimed to test whether improving systemic insulin sensitiv...

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Detalles Bibliográficos
Autores principales: Izquierdo, María Concepción, Harris, Michael, Shanmugarajah, Niroshan, Zhong, Kendra, Ozcan, Lale, Fredman, Gabrielle, Haeusler, Rebecca A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614776/
https://www.ncbi.nlm.nih.gov/pubmed/37905094
http://dx.doi.org/10.1101/2023.10.14.562366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614776/
https://www.ncbi.nlm.nih.gov/pubmed/37905094
http://dx.doi.org/10.1101/2023.10.14.562366

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