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Insulin sensitization by hepatic FoxO deletion is insufficient to lower atherosclerosis in mice
BACKGROUND–: Type 2 diabetes is associated with an increased risk of atherosclerotic cardiovascular disease. It has been suggested that insulin resistance underlies this link, possibly by altering the functions of cells in the artery wall. We aimed to test whether improving systemic insulin sensitiv...
Autores principales: | Izquierdo, María Concepción, Harris, Michael, Shanmugarajah, Niroshan, Zhong, Kendra, Ozcan, Lale, Fredman, Gabrielle, Haeusler, Rebecca A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614776/ https://www.ncbi.nlm.nih.gov/pubmed/37905094 http://dx.doi.org/10.1101/2023.10.14.562366 |
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