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The rotavirus VP5*/VP8* conformational transition permeabilizes membranes to Ca(2+)

Rotaviruses infect cells by delivering into the cytosol a transcriptionally active inner capsid particle (a "double-layer particle": DLP). Delivery is the function of a third, outer layer, which drives uptake from the cell surface into small vesicles from which the DLPs escape. In publishe...

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Detalles Bibliográficos
Autores principales: De Sautu, Marilina, Herrmann, Tobias, Jenni, Simon, Harrison, Stephen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614792/
https://www.ncbi.nlm.nih.gov/pubmed/37905109
http://dx.doi.org/10.1101/2023.10.15.562449