Insights into Drug Cardiotoxicity from Biological and Chemical Data: The First Public Classifiers for FDA DICTrank

Drug-induced cardiotoxicity (DICT) is a major concern in drug development, accounting for 10–14% of postmarket withdrawals. In this study, we explored the capabilities of various chemical and biological data to predict cardiotoxicity, using the recently released Drug-Induced Cardiotoxicity Rank (DIC...

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Detalles Bibliográficos
Autores principales: Seal, Srijit, Spjuth, Ola, Hosseini-Gerami, Layla, García-Ortegón, Miguel, Singh, Shantanu, Bender, Andreas, Carpenter, Anne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614794/
https://www.ncbi.nlm.nih.gov/pubmed/37905146
http://dx.doi.org/10.1101/2023.10.15.562398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614794/
https://www.ncbi.nlm.nih.gov/pubmed/37905146
http://dx.doi.org/10.1101/2023.10.15.562398

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