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Explainable protein function annotation using local structure embeddings

The rapid expansion of protein sequence and structure databases has resulted in a significant number of proteins with ambiguous or unknown function. While advances in machine learning techniques hold great potential to fill this annotation gap, current methods for function prediction are unable to a...

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Detalles Bibliográficos
Autores principales: Derry, Alexander, Altman, Russ B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614799/
https://www.ncbi.nlm.nih.gov/pubmed/37905033
http://dx.doi.org/10.1101/2023.10.13.562298