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Machine Learning Strategies for Improved Phenotype Prediction in Underrepresented Populations

Precision medicine models often perform better for populations of European ancestry due to the over-representation of this group in the genomic datasets and large-scale biobanks from which the models are constructed. As a result, prediction models may misrepresent or provide less accurate treatment...

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Detalles Bibliográficos
Autores principales: Bonet, David, Levin, May, Montserrat, Daniel Mas, Ioannidis, Alexander G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614800/
https://www.ncbi.nlm.nih.gov/pubmed/37904983
http://dx.doi.org/10.1101/2023.10.12.561949