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Development of covalent chemogenetic K(2P) channel activators
K(2P) potassium channels regulate excitability by affecting cellular resting membrane potential in the brain, cardiovascular system, immune cells, and sensory organs. Despite their important roles in anesthesia, arrhythmia, pain, hypertension, sleep, and migraine, the ability to control K(2P) functi...
Autores principales: | Deal, Parker E., Lee, Haerim, Mondal, Abhisek, Lolicato, Marco, de Mendonca, Philipe Ribeiro Furtado, Black, Holly, El-Hilali, Xochina, Bryant, Clifford, Isacoff, Ehud Y., Renslo, Adam R., Minor, Daniel L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614804/ https://www.ncbi.nlm.nih.gov/pubmed/37905049 http://dx.doi.org/10.1101/2023.10.15.561774 |
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