ChEC-seq2: an improved Chromatin Endogenous Cleavage sequencing method and bioinformatic analysis pipeline for mapping in vivo protein-DNA interactions

Defining the in vivo DNA binding specificity of transcription factors (TFs) has relied nearly exclusively on chromatin immunoprecipitation (ChIP). While ChIP reveals TF binding patterns, its resolution is low. Higher resolution methods employing nucleases such as ChIP-exo, chromatin endogenous cleav...

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Detalles Bibliográficos
Autores principales: VanBelzen, Jake, Duan, Chengzhe, Brickner, Donna Garvey, Brickner, Jason H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614805/
https://www.ncbi.nlm.nih.gov/pubmed/37905156
http://dx.doi.org/10.1101/2023.10.15.562421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614805/
https://www.ncbi.nlm.nih.gov/pubmed/37905156
http://dx.doi.org/10.1101/2023.10.15.562421

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