Bayesian inference of relative fitness on high-throughput pooled competition assays

The tracking of lineage frequencies via DNA barcode sequencing enables the quantification of microbial fitness. However, experimental noise coming from biotic and abiotic sources complicates the computation of a reliable inference. We present a Bayesian pipeline to infer relative microbial fitness f...

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Detalles Bibliográficos
Autores principales: Razo-Mejia, Manuel, Mani, Madhav, Petrov, Dmitri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614806/
https://www.ncbi.nlm.nih.gov/pubmed/37904971
http://dx.doi.org/10.1101/2023.10.14.562365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614806/
https://www.ncbi.nlm.nih.gov/pubmed/37904971
http://dx.doi.org/10.1101/2023.10.14.562365

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