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Bayesian inference of relative fitness on high-throughput pooled competition assays
The tracking of lineage frequencies via DNA barcode sequencing enables the quantification of microbial fitness. However, experimental noise coming from biotic and abiotic sources complicates the computation of a reliable inference. We present a Bayesian pipeline to infer relative microbial fitness f...
Autores principales: | Razo-Mejia, Manuel, Mani, Madhav, Petrov, Dmitri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614806/ https://www.ncbi.nlm.nih.gov/pubmed/37904971 http://dx.doi.org/10.1101/2023.10.14.562365 |
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