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The Interferon-inducible NAMPT acts as a protein phosphoribosylase to restrict viral infection
As obligate intracellular pathogens, viruses often activate host metabolic enzymes to supply intermediates that support progeny production. Nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme of the salvage NAD(+) synthesis, is an interferon-inducible protein that inhibits the r...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614811/ https://www.ncbi.nlm.nih.gov/pubmed/37905103 http://dx.doi.org/10.1101/2023.10.12.562112 |