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The Interferon-inducible NAMPT acts as a protein phosphoribosylase to restrict viral infection

As obligate intracellular pathogens, viruses often activate host metabolic enzymes to supply intermediates that support progeny production. Nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme of the salvage NAD(+) synthesis, is an interferon-inducible protein that inhibits the r...

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Detalles Bibliográficos
Autores principales: Zhang, Shu, Xie, Na, Liu, Yongzhen, Qin, Chao, Savas, Ali Can, Wang, Ting-Yu, Li, Shutong, Rao, Youliang, Shambayate, Alexandra, Chou, Tsui-Fen, Brenner, Charles, Huang, Canhua, Feng, Pinghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614811/
https://www.ncbi.nlm.nih.gov/pubmed/37905103
http://dx.doi.org/10.1101/2023.10.12.562112