Negative Binomial Mixture Model for Identification of Noise in Antigen-Specificity Predictions by LIBRA-seq

MOTIVATION: LIBRA-seq (linking B cell receptor to antigen specificity by sequencing) provides a powerful tool for interrogating the antigen-specific B cell compartment and identifying antibodies against antigen targets of interest. Identification of noise in LIBRA-seq antigen count data is critical...

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Detalles Bibliográficos
Autores principales: Wasdin, Perry T., Abu-Shmais, Alexandra A., Irvin, Michael W., Vukovich, Matthew J., Georgiev, Ivelin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614817/
https://www.ncbi.nlm.nih.gov/pubmed/37904915
http://dx.doi.org/10.1101/2023.10.13.562258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614817/
https://www.ncbi.nlm.nih.gov/pubmed/37904915
http://dx.doi.org/10.1101/2023.10.13.562258

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