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Negative Binomial Mixture Model for Identification of Noise in Antigen-Specificity Predictions by LIBRA-seq
MOTIVATION: LIBRA-seq (linking B cell receptor to antigen specificity by sequencing) provides a powerful tool for interrogating the antigen-specific B cell compartment and identifying antibodies against antigen targets of interest. Identification of noise in LIBRA-seq antigen count data is critical...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614817/ https://www.ncbi.nlm.nih.gov/pubmed/37904915 http://dx.doi.org/10.1101/2023.10.13.562258 |