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Population variability in X-chromosome inactivation across 9 mammalian species

One of the two X chromosomes in female mammals is epigenetically silenced in embryonic stem cells by X chromosome inactivation (XCI). This creates a mosaic of cells expressing either the maternal or the paternal X allele. The XCI ratio, the proportion of inactivated parental alleles, varies widely a...

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Detalles Bibliográficos
Autores principales: Werner, Jonathan M., Hover, John, Gillis, Jesse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614859/
https://www.ncbi.nlm.nih.gov/pubmed/37904929
http://dx.doi.org/10.1101/2023.10.17.562732