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Population variability in X-chromosome inactivation across 9 mammalian species

One of the two X chromosomes in female mammals is epigenetically silenced in embryonic stem cells by X chromosome inactivation (XCI). This creates a mosaic of cells expressing either the maternal or the paternal X allele. The XCI ratio, the proportion of inactivated parental alleles, varies widely a...

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Detalles Bibliográficos
Autores principales:	Werner, Jonathan M., Hover, John, Gillis, Jesse
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614859/ https://www.ncbi.nlm.nih.gov/pubmed/37904929 http://dx.doi.org/10.1101/2023.10.17.562732

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