An optimized high-yield protocol for expression and purification of monomeric full-length BAX protein

Diverse developmental signals and pro-death stresses converge on regulation of the mitochondrial pathway of apoptosis. BAX, a pro-apoptotic BCL-2 effector, directly forms proteolipid pores in the outer mitochondrial member to activate the mitochondrial pathway of apoptosis. BAX is a viable pharmacol...

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Detalles Bibliográficos
Autores principales: Chen, Yiyang, Gelles, Jesse D., Mohammed, Jarvier N., Chipuk, Jerry Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614868/
https://www.ncbi.nlm.nih.gov/pubmed/37905126
http://dx.doi.org/10.1101/2023.10.16.562589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614868/
https://www.ncbi.nlm.nih.gov/pubmed/37905126
http://dx.doi.org/10.1101/2023.10.16.562589

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