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Nanomechanics of wild-type and mutant dimers of the tip-link protein protocadherin 15
Mechanical force controls the opening and closing of mechanosensitive ion channels atop the hair bundles of the inner ear. The filamentous tip link connecting transduction channels to the tallest neighboring stereocilium modulates the force transmitted to the channels and thus changes their probabil...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614884/ https://www.ncbi.nlm.nih.gov/pubmed/37905108 http://dx.doi.org/10.1101/2023.10.17.562769 |