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Membrane Mimetic-Dependence of GPCR Energy Landscapes
Protein function strongly depends on temperature, which is related to temperature-dependent changes in the equilibria of protein conformational states. We leveraged variable-temperature (19)F-NMR spectroscopy to interrogate the temperature dependence of the conformational landscape of the human A(2A...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614885/ https://www.ncbi.nlm.nih.gov/pubmed/37905159 http://dx.doi.org/10.1101/2023.10.16.562552 |