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Membrane Mimetic-Dependence of GPCR Energy Landscapes

Protein function strongly depends on temperature, which is related to temperature-dependent changes in the equilibria of protein conformational states. We leveraged variable-temperature (19)F-NMR spectroscopy to interrogate the temperature dependence of the conformational landscape of the human A(2A...

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Detalles Bibliográficos
Autores principales:	Thakur, Naveen, Ray, Arka Prabha, Lyman, Edward, Gao, Zhan-Guo, Jacobson, Kenneth A., Eddy, Matthew T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614885/ https://www.ncbi.nlm.nih.gov/pubmed/37905159 http://dx.doi.org/10.1101/2023.10.16.562552

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