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T-cell commitment inheritance – an agent-based multi-scale model

T-cell development provides an excellent model system for studying lineage commitment from a multipotent progenitor. The intrathymic development process has been thoroughly studied. The molecular circuitry controlling it has been dissected and the necessary steps like programmed shut off of progenit...

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Detalles Bibliográficos
Autores principales: Andersson, Emil, Rothenberg, Ellen V., Peterson, Carsten, Olariu, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614897/
https://www.ncbi.nlm.nih.gov/pubmed/37905091
http://dx.doi.org/10.1101/2023.10.18.562905