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Exceptional longevity of mammalian ovarian and oocyte macromolecules throughout the reproductive lifespan

The mechanisms contributing to age-related deterioration of the female reproductive system are complex, however aberrant protein homeostasis is a major contributor. We elucidated exceptionally stable proteins, structures, and macromolecules that persist in mammalian ovaries and gametes across the re...

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Detalles Bibliográficos
Autores principales: Bomba-Warczak, Ewa K., Velez, Karen M., Zhou, Luhan T, Guillermier, Christelle, Edassery, Seby, Steinhauser, Matthew, Savas, Jeffrey N., Duncan, Francesca E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614913/
https://www.ncbi.nlm.nih.gov/pubmed/37905022
http://dx.doi.org/10.1101/2023.10.18.562852