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The structural OFF and ON states of myosin can be decoupled from the biochemical super-relaxed and disordered-relaxed states
There is a growing awareness that both thick filament and classical thin filament regulation play central roles in modulating muscle contraction. Myosin ATPase assays have demonstrated that under relaxed conditions, myosin may reside in either a high energy-consuming disordered-relaxed (DRX) state a...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614925/ https://www.ncbi.nlm.nih.gov/pubmed/37904972 http://dx.doi.org/10.1101/2023.10.18.562891 |