The structural OFF and ON states of myosin can be decoupled from the biochemical super-relaxed and disordered-relaxed states

There is a growing awareness that both thick filament and classical thin filament regulation play central roles in modulating muscle contraction. Myosin ATPase assays have demonstrated that under relaxed conditions, myosin may reside in either a high energy-consuming disordered-relaxed (DRX) state a...

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Detalles Bibliográficos
Autores principales: Ma, Weikang, Jani, Vivek P., Song, Taejeong, Gao, Chengqian, Gong, Henry, Sadayappan, Sakthivel, Kass, David A., Irving, Thomas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614925/
https://www.ncbi.nlm.nih.gov/pubmed/37904972
http://dx.doi.org/10.1101/2023.10.18.562891

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