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On the problem of inflation in transcriptome-wide association studies
Hundreds of thousands of loci have been associated with complex traits via genome-wide association studies (GWAS), but an understanding of the mechanistic connection between GWAS loci and disease remains elusive. Genetic predictors of molecular traits are useful for identifying the mediating roles o...
Autores principales: | Liang, Yanyu, Nyasimi, Festus, Im, Hae Kyung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614931/ https://www.ncbi.nlm.nih.gov/pubmed/37904952 http://dx.doi.org/10.1101/2023.10.17.562831 |
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