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Multi-pass, single-molecule nanopore reading of long protein strands with single-amino acid sensitivity
The ability to sequence single protein molecules in their native, full-length form would enable a more comprehensive understanding of proteomic diversity. Current technologies, however, are limited in achieving this goal. Here, we establish a method for long-range, single-molecule reading of intact...
Autores principales: | Motone, Keisuke, Kontogiorgos-Heintz, Daphne, Wee, Jasmine, Kurihara, Kyoko, Yang, Sangbeom, Roote, Gwendolin, Fang, Yishu, Cardozo, Nicolas, Nivala, Jeff |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614977/ https://www.ncbi.nlm.nih.gov/pubmed/37905023 http://dx.doi.org/10.1101/2023.10.19.563182 |
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