ROCK1 activates mitochondrial fission leading to oxidative stress and muscle atrophy

Chronic kidney disease (CKD) is often associated with protein-energy wasting (PEW), which is characterized by a reduction in muscle mass and strength. Although mitochondrial dysfunction and oxidative stress have been implicated to play a role in the pathogenesis of muscle wasting, the underlying mec...

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Detalles Bibliográficos
Autores principales: Si, Meijun, Yu, Rizhen, Lin, Hongchun, Li, Feng, Jung, Sungyun, Thomas, Sandhya S., Danesh, Farhard S, Wang, Yanlin, Peng, Hui, Hu, Zhaoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614981/
https://www.ncbi.nlm.nih.gov/pubmed/37905139
http://dx.doi.org/10.1101/2023.10.22.563469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614981/
https://www.ncbi.nlm.nih.gov/pubmed/37905139
http://dx.doi.org/10.1101/2023.10.22.563469

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