Cargando…
ROCK1 activates mitochondrial fission leading to oxidative stress and muscle atrophy
Chronic kidney disease (CKD) is often associated with protein-energy wasting (PEW), which is characterized by a reduction in muscle mass and strength. Although mitochondrial dysfunction and oxidative stress have been implicated to play a role in the pathogenesis of muscle wasting, the underlying mec...
Autores principales: | Si, Meijun, Yu, Rizhen, Lin, Hongchun, Li, Feng, Jung, Sungyun, Thomas, Sandhya S., Danesh, Farhard S, Wang, Yanlin, Peng, Hui, Hu, Zhaoyong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614981/ https://www.ncbi.nlm.nih.gov/pubmed/37905139 http://dx.doi.org/10.1101/2023.10.22.563469 |
Ejemplares similares
-
Reprogramming of cis-regulatory networks during skeletal muscle atrophy in male mice
por: Lin, Hongchun, et al.
Publicado: (2023) -
Suppression of muscle wasting by the plant‐derived compound ursolic acid in a model of chronic kidney disease
por: Yu, Rizhen, et al.
Publicado: (2016) -
Long‐noncoding RNA Atrolnc‐1 promotes muscle wasting in mice with chronic kidney disease
por: Sun, Lijing, et al.
Publicado: (2018) -
Decoding the transcriptome of denervated muscle at single‐nucleus resolution
por: Lin, Hongchun, et al.
Publicado: (2022) -
ROCK1 reduces mitochondrial content and irisin production in muscle suppressing adipocyte browning and impairing insulin sensitivity
por: Zhou, Xiaoshuang, et al.
Publicado: (2016)