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Regional quantification of cardiac metabolism with hyperpolarized [1-(13)C]-pyruvate MRI evaluated in an oral glucose challenge

BACKGROUND: The heart has metabolic flexibility, which is influenced by fed/fasting states, and pathologies such as myocardial ischemia and hypertrophic cardiomyopathy (HCM). Hyperpolarized (HP) (13)C-pyruvate MRI is a promising new tool for non-invasive quantification of myocardial glycolytic and K...

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Detalles Bibliográficos
Autores principales: Larson, Peder E. Z., Tang, Shuyu, Liu, Xiaoxi, Sinha, Avantika, Dwork, Nicholas, Sivalokanathan, Sanjay, Liu, Jing, Bok, Robert, Ordovas, Karen G., Slater, James, Gordon, Jeremy W., Abraham, M. Roselle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615005/
https://www.ncbi.nlm.nih.gov/pubmed/37904936
http://dx.doi.org/10.1101/2023.10.16.23297052