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Sigma1 Regulates Lipid Droplet–Mediated Redox Homeostasis Required for Prostate Cancer Proliferation

Lipid droplets (LD) are dynamic organelles that serve as hubs of cellular metabolic processes. Emerging evidence shows that LDs also play a critical role in maintaining redox homeostasis and can mitigate lipid oxidative stress. In multiple cancers, including prostate cancer, LD accumulation is assoc...

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Detalles Bibliográficos
Autores principales: Oyer, Halley M., Steck, Alexandra R., Longen, Charles G., Venkat, Sanjana, Bayrak, Konuralp, Munger, Eleanor B., Fu, Dan, Castagnino, Paola A., Sanders, Christina M., Tancler, Nathalia A., Mai, My T., Myers, Justin P., Schiewer, Matthew J., Chen, Nan, Mostaghel, Elahe A., Kim, Felix J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615122/
https://www.ncbi.nlm.nih.gov/pubmed/37874216
http://dx.doi.org/10.1158/2767-9764.CRC-22-0371