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Sigma1 Regulates Lipid Droplet–Mediated Redox Homeostasis Required for Prostate Cancer Proliferation
Lipid droplets (LD) are dynamic organelles that serve as hubs of cellular metabolic processes. Emerging evidence shows that LDs also play a critical role in maintaining redox homeostasis and can mitigate lipid oxidative stress. In multiple cancers, including prostate cancer, LD accumulation is assoc...
Autores principales: | Oyer, Halley M., Steck, Alexandra R., Longen, Charles G., Venkat, Sanjana, Bayrak, Konuralp, Munger, Eleanor B., Fu, Dan, Castagnino, Paola A., Sanders, Christina M., Tancler, Nathalia A., Mai, My T., Myers, Justin P., Schiewer, Matthew J., Chen, Nan, Mostaghel, Elahe A., Kim, Felix J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615122/ https://www.ncbi.nlm.nih.gov/pubmed/37874216 http://dx.doi.org/10.1158/2767-9764.CRC-22-0371 |
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