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Local Myeloid-Derived Suppressor Cells Impair Progression of Experimental Autoimmune Uveitis by Alleviating Oxidative Stress and Inflammation

PURPOSE: To evaluate the immune regulatory effect of human cord blood myeloid-derived suppressor cells (MDSCs) in experimental autoimmune uveitis (EAU) models. METHODS: MDSCs (1 × 10(6)) or PBS were injected into established C57BL/6 EAU mice via the subconjunctival route on days 0 and 7. The severit...

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Detalles Bibliográficos
Autores principales: Lee, Jae-Young, Kim, Sueon, Sohn, Hyun-Jung, Kim, Chang-Hyun, Kim, Tai-Gyu, Lee, Hyun Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615146/
https://www.ncbi.nlm.nih.gov/pubmed/37878302
http://dx.doi.org/10.1167/iovs.64.13.39