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Attenuating Neuronal Autophagy Alleviates Inflammatory Injury in OGDDeprived Co-culture of HT22 with BV2

Neuronal CX3CL1 suppressed microglial inflammation by binding to its receptor CX3CR1 expressed on microglia. Neuronal autophagy was prominently activated by cerebral ischemia, whereas CX3CL1 expression in autophagic neurons was conversely down-regulated to exacerbate microglial inflammation. Accordi...

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Detalles Bibliográficos
Autores principales: Huang, Z. W., Liu, Y. Y., Chen, X. M., Yu, C. L., He, H. Y., Deng, Y. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615190/
https://www.ncbi.nlm.nih.gov/pubmed/37908770
http://dx.doi.org/10.32607/actanaturae.11830