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Targeted randomization dose optimization trials enable fractional dosing of scarce drugs
Administering drug at a dose lower than that used in pivotal clinical trials, known as fractional dosing, can stretch scarce resources. Implementing fractional dosing with confidence requires understanding a drug’s dose-response relationship. Clinical trials aimed at describing dose-response in scar...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615276/ https://www.ncbi.nlm.nih.gov/pubmed/37903093 http://dx.doi.org/10.1371/journal.pone.0287511 |