The anti-platelet drug cilostazol enhances heart rate and interrenal steroidogenesis and exerts a scant effect on innate immune responses in zebrafish

RATIONALE: Cilostazol, an anti-platelet phosphodiesterase-3 inhibitor used for the treatment of intermittent claudication, is known for its pleiotropic effects on platelets, endothelial cells and smooth muscle cells. However, how cilostazol impacts the endocrine system and the injury-induced inflamm...

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Detalles Bibliográficos
Autores principales: Chang, Wei-Chun, Chen, Mei-Jen, Hsiao, Chung-Der, Hu, Rong-Ze, Huang, Yu-Shan, Chen, Yu-Fu, Yang, Tsai-Hua, Tsai, Guan-Yi, Chou, Chih-Wei, Chen, Ren-Shiang, Chuang, Yung-Jen, Liu, Yi-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615288/
https://www.ncbi.nlm.nih.gov/pubmed/37903128
http://dx.doi.org/10.1371/journal.pone.0292858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615288/
https://www.ncbi.nlm.nih.gov/pubmed/37903128
http://dx.doi.org/10.1371/journal.pone.0292858

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