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The anti-platelet drug cilostazol enhances heart rate and interrenal steroidogenesis and exerts a scant effect on innate immune responses in zebrafish
RATIONALE: Cilostazol, an anti-platelet phosphodiesterase-3 inhibitor used for the treatment of intermittent claudication, is known for its pleiotropic effects on platelets, endothelial cells and smooth muscle cells. However, how cilostazol impacts the endocrine system and the injury-induced inflamm...
Autores principales: | Chang, Wei-Chun, Chen, Mei-Jen, Hsiao, Chung-Der, Hu, Rong-Ze, Huang, Yu-Shan, Chen, Yu-Fu, Yang, Tsai-Hua, Tsai, Guan-Yi, Chou, Chih-Wei, Chen, Ren-Shiang, Chuang, Yung-Jen, Liu, Yi-Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615288/ https://www.ncbi.nlm.nih.gov/pubmed/37903128 http://dx.doi.org/10.1371/journal.pone.0292858 |
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