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CCR1 mediates Müller cell activation and photoreceptor cell death in macular and retinal degeneration

Mononuclear cells are involved in the pathogenesis of retinal diseases, including age-related macular degeneration (AMD). Here, we examined the mechanisms that underlie macrophage-driven retinal cell death. Monocytes were extracted from patients with AMD and differentiated into macrophages (hMdɸs),...

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Detalles Bibliográficos
Autores principales: Elbaz-Hayoun, Sarah, Rinsky, Batya, Hagbi-Levi, Shira, Grunin, Michelle, Chowers, Itay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615370/
https://www.ncbi.nlm.nih.gov/pubmed/37903056
http://dx.doi.org/10.7554/eLife.81208