Mechanism of action of IC 100, a humanized IgG4 monoclonal antibody targeting apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC)

Inflammasomes are multiprotein complexes of the innate immune response that recognize a diverse range of intracellular sensors of infection or cell damage and recruit the adaptor protein apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC) into an inflammasome signal...

Descripción completa

Detalles Bibliográficos
Autores principales: de Rivero Vaccari, Juan Pablo, Mim, Carsten, Hadad, Roey, Cyr, Brianna, Stefansdottir, Thorunn Anna, Keane, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615563/
https://www.ncbi.nlm.nih.gov/pubmed/35793783
http://dx.doi.org/10.1016/j.trsl.2022.06.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615563/
https://www.ncbi.nlm.nih.gov/pubmed/35793783
http://dx.doi.org/10.1016/j.trsl.2022.06.016

Ejemplares similares