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Curative Effect of AD-MSCs against Cisplatin-Induced Hepatotoxicity in Rats is Potentiated by Azilsartan: Targeting Oxidative Stress, MAPK, and Apoptosis Signaling Pathways

Despite its clinical value, cisplatin (CISP) is complicated by marked hepatotoxicity via inducing oxidative stress, inflammatory, and apoptotic pathways. This study aims to explore the protective impact of azilsartan (AZIL), an antihypertensive drug, in addition to adipose tissue-derived mesenchymal...

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Detalles Bibliográficos
Autores principales: Bekhit, Amany Abdlrehim, Beshay, Olivia N., Fawzy, Michael A., Abdel-Hafez, Sara Mohamed Naguib, Batiha, Gaber El-Saber, Ataya, Farid S., Fathy, Moustafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615573/
https://www.ncbi.nlm.nih.gov/pubmed/37908315
http://dx.doi.org/10.1155/2023/6767735