Sensitive Measurement of Clinically Relevant Factor VIII Levels in Thrombin Generation Assays Requires Presence of Factor XIa

Background  Hemophilia A (HA) is characterized by decreased or absent factor VIII (FVIII) activity. Current FVIII assays are based on clotting time and thus only provide information about the initiation of coagulation. In contrast, thrombin generation assays (TGAs) can be used to measure the full co...

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Detalles Bibliográficos
Autores principales: van de Berg, Tom W., Beckers, Erik A. M., Heubel-Moenen, Floor C. J. I., Henskens, Yvonne M. C., Thomassen, M. Christella L. G. D., Hackeng, Tilman M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615588/
https://www.ncbi.nlm.nih.gov/pubmed/37236229
http://dx.doi.org/10.1055/a-2101-7961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615588/
https://www.ncbi.nlm.nih.gov/pubmed/37236229
http://dx.doi.org/10.1055/a-2101-7961

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