Long-term persistence of transcriptionally active ‘defective’ HIV-1 proviruses: implications for persistent immune activation during antiretroviral therapy

OBJECTIVES: People with HIV-1 (PWH) on effective antiretroviral therapy (ART) continue to exhibit chronic systemic inflammation, immune activation, and persistent elevations in markers of HIV-1 infection [including HIV-DNA, cell-associated HIV-RNA (CA HIV-RNA), and antibodies to HIV-1 proteins] desp...

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Detalles Bibliográficos
Autores principales: Singh, Kanal, Natarajan, Ven, Dewar, Robin, Rupert, Adam, Badralmaa, Yuden, Zhai, Tracey, Winchester, Nicole, Scrimieri, Francesca, Smith, Mindy, Davis, Ivery, Lallemand, Perrine, Giglietti, Aude, Hensien, Jack, Buerkert, Thomas, Goshu, Bruktawit, Rehm, Catherine A., Hu, Zonghui, Lane, H. Clifford, Imamichi, Hiromi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615727/
https://www.ncbi.nlm.nih.gov/pubmed/37555786
http://dx.doi.org/10.1097/QAD.0000000000003667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615727/
https://www.ncbi.nlm.nih.gov/pubmed/37555786
http://dx.doi.org/10.1097/QAD.0000000000003667

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