GWAS-identified bipolar disorder risk allele in the FADS1/2 gene region links mood episodes and unsaturated fatty acid metabolism in mutant mice

Large-scale genome-wide association studies (GWASs) on bipolar disorder (BD) have implicated the involvement of the fatty acid desaturase (FADS) locus. These enzymes (FADS1 and FADS2) are involved in the metabolism of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which are thought to p...

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Detalles Bibliográficos
Autores principales: Yamamoto, Hirona, Lee-Okada, Hyeon-Cheol, Ikeda, Masashi, Nakamura, Takumi, Saito, Takeo, Takata, Atsushi, Yokomizo, Takehiko, Iwata, Nakao, Kato, Tadafumi, Kasahara, Takaoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Immediate Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615742/
https://www.ncbi.nlm.nih.gov/pubmed/36806390
http://dx.doi.org/10.1038/s41380-023-01988-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615742/
https://www.ncbi.nlm.nih.gov/pubmed/36806390
http://dx.doi.org/10.1038/s41380-023-01988-2

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