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Multi-ancestry meta-analysis and fine-mapping in Alzheimer’s disease

Genome-wide association studies (GWAS) of Alzheimer’s disease are predominantly carried out in European ancestry individuals despite the known variation in genetic architecture and disease prevalence across global populations. We leveraged published GWAS summary statistics from European, East Asian,...

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Detalles Bibliográficos
Autores principales: Lake, Julie, Warly Solsberg, Caroline, Kim, Jonggeol Jeffrey, Acosta-Uribe, Juliana, Makarious, Mary B., Li, Zizheng, Levine, Kristin, Heutink, Peter, Alvarado, Chelsea X., Vitale, Dan, Kang, Sarang, Gim, Jungsoo, Lee, Kun Ho, Pina-Escudero, Stefanie D., Ferrucci, Luigi, Singleton, Andrew B., Blauwendraat, Cornelis, Nalls, Mike A., Yokoyama, Jennifer S., Leonard, Hampton L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615750/
https://www.ncbi.nlm.nih.gov/pubmed/37198259
http://dx.doi.org/10.1038/s41380-023-02089-w