Transcriptional and functional effects of lithium in bipolar disorder iPSC-derived cortical spheroids

Lithium (Li) is recommended for long-term treatment of bipolar disorder (BD). However, its mechanism of action is still poorly understood. Induced pluripotent stem cell (iPSC)-derived brain organoids have emerged as a powerful tool for modeling BD-related disease mechanisms. We studied the effects o...

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Detalles Bibliográficos
Autores principales: Osete, Jordi Requena, Akkouh, Ibrahim A., Ievglevskyi, Oleksandr, Vandenberghe, Matthieu, de Assis, Denis Reis, Ueland, Thor, Kondratskaya, Elena, Holen, Børge, Szabo, Attila, Hughes, Timothy, Smeland, Olav B., Steen, Vidar Martin, Andreassen, Ole A., Djurovic, Srdjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615757/
https://www.ncbi.nlm.nih.gov/pubmed/36653674
http://dx.doi.org/10.1038/s41380-023-01944-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615757/
https://www.ncbi.nlm.nih.gov/pubmed/36653674
http://dx.doi.org/10.1038/s41380-023-01944-0

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