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Proteomics reveal biomarkers for diagnosis, disease activity and long-term disability outcomes in multiple sclerosis

Sensitive and reliable protein biomarkers are needed to predict disease trajectory and personalize treatment strategies for multiple sclerosis (MS). Here, we use the highly sensitive proximity-extension assay combined with next-generation sequencing (Olink Explore) to quantify 1463 proteins in cereb...

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Detalles Bibliográficos
Autores principales: Åkesson, Julia, Hojjati, Sara, Hellberg, Sandra, Raffetseder, Johanna, Khademi, Mohsen, Rynkowski, Robert, Kockum, Ingrid, Altafini, Claudio, Lubovac-Pilav, Zelmina, Mellergård, Johan, Jenmalm, Maria C., Piehl, Fredrik, Olsson, Tomas, Ernerudh, Jan, Gustafsson, Mika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616092/
https://www.ncbi.nlm.nih.gov/pubmed/37903821
http://dx.doi.org/10.1038/s41467-023-42682-9