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Integrated analysis of histone lysine lactylation (Kla)-specific genes suggests that NR6A1, OSBP2 and UNC119B are novel therapeutic targets for hepatocellular carcinoma

Histone lysine lactylation (Kla) plays a vital role in the tumorigenesis of hepatocellular carcinoma (HCC). Hence, we focused on Kla-specific genes to select novel therapeutic targets. Differentially expressed Kla-specific genes (DEKlaGs) were identified from TCGA with the cut-off criteria |log(2)(F...

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Detalles Bibliográficos
Autores principales: Wu, Qinjuan, Li, Xin, Long, Menghong, Xie, Xianfeng, Liu, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616101/
https://www.ncbi.nlm.nih.gov/pubmed/37903971
http://dx.doi.org/10.1038/s41598-023-46057-4