Optogenetic control of YAP reveals a dynamic communication code for stem cell fate and proliferation

YAP is a transcriptional regulator that controls pluripotency, cell fate, and proliferation. How cells ensure the selective activation of YAP effector genes is unknown. This knowledge is essential to rationally control cellular decision-making. Here we leverage optogenetics, live-imaging of transcri...

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Detalles Bibliográficos
Autores principales: Meyer, Kirstin, Lammers, Nicholas C., Bugaj, Lukasz J., Garcia, Hernan G., Weiner, Orion D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616176/
https://www.ncbi.nlm.nih.gov/pubmed/37903793
http://dx.doi.org/10.1038/s41467-023-42643-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616176/
https://www.ncbi.nlm.nih.gov/pubmed/37903793
http://dx.doi.org/10.1038/s41467-023-42643-2

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