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Optogenetic control of YAP reveals a dynamic communication code for stem cell fate and proliferation
YAP is a transcriptional regulator that controls pluripotency, cell fate, and proliferation. How cells ensure the selective activation of YAP effector genes is unknown. This knowledge is essential to rationally control cellular decision-making. Here we leverage optogenetics, live-imaging of transcri...
Autores principales: | Meyer, Kirstin, Lammers, Nicholas C., Bugaj, Lukasz J., Garcia, Hernan G., Weiner, Orion D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616176/ https://www.ncbi.nlm.nih.gov/pubmed/37903793 http://dx.doi.org/10.1038/s41467-023-42643-2 |
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