Achieving quantitative reproducibility in label-free multisite DIA experiments through multirun alignment

DIA is a mainstream method for quantitative proteomics, but consistent quantification across multiple LC-MS/MS instruments remains a bottleneck in parallelizing data acquisition. One reason for this inconsistency and missing quantification is the retention time shift which current software does not...

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Detalles Bibliográficos
Autores principales: Gupta, Shubham, Sing, Justin C., Röst, Hannes L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616189/
https://www.ncbi.nlm.nih.gov/pubmed/37903988
http://dx.doi.org/10.1038/s42003-023-05437-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616189/
https://www.ncbi.nlm.nih.gov/pubmed/37903988
http://dx.doi.org/10.1038/s42003-023-05437-2

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