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Achieving quantitative reproducibility in label-free multisite DIA experiments through multirun alignment
DIA is a mainstream method for quantitative proteomics, but consistent quantification across multiple LC-MS/MS instruments remains a bottleneck in parallelizing data acquisition. One reason for this inconsistency and missing quantification is the retention time shift which current software does not...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616189/ https://www.ncbi.nlm.nih.gov/pubmed/37903988 http://dx.doi.org/10.1038/s42003-023-05437-2 |